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Phytochemical screening and in vitro antioxidant assays in Foeniculum vulgare Mill. (Fennel) seeds collected from Tarai region in the Uttarakhand

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Title Phytochemical screening and in vitro antioxidant assays in Foeniculum vulgare Mill. (Fennel) seeds collected from Tarai region in the Uttarakhand
 
Creator Mehra, Nisha
Tamta, Garima
Nand, Viveka
 
Subject Antioxidants
DPPH scavenging
Fennel
Metal chelation scavenging
Phytochemicals
Superoxide scavenging
 
Description 213-222
Fennel is a culinary spice of Apiaceae family. The objective of present study to evaluate the antioxidant potential and
phytochemical screening in terms of phenolic content, flavonoid content, orthodihydric phenolic content, proanthocyanidin, and
total tannin content in hexane, chloroform, and methanol extract of Foeniculum vulgare seeds. Maximum DPPH scavenging
activity exhibited in the hexane extract of FNL-PM (IC50= 443.88±0.91 μg/mL). Maximum hydroxyl radical scavenging
activity observed in methanol extract of FNL-117 (IC50= 414.74±1.35 μg/mL). Higher superoxide radical scavenging activity
exhibited in the hexane extract of FNL-126 (IC50= 420.68±1.09 μg/mL) and nitric oxide radical scavenging in the hexane
extract of FNL-117 (IC50= 557.03±0.86 μg/mL). Strong metal chelation activity observed in hexane extract of FNL-118
(IC50= 563.07±0.07 μg/mL). Higher phytochemicals are observed in methanol extract of FNL-120. The present study also
revealed the similarities that exist between fennel seeds on the basis of antioxidant potency and phytochemicals through a
statistical approach i.e., cluster analysis using dendrogram, regarding genetic makeup of fennel cultivars so that future research
will be carried out to develop a new variety of fennel for further implementation in pharma industries.
 
Date 2022-08-11T05:46:38Z
2022-08-11T05:46:38Z
2022-06
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/60263
https://doi.org/10.56042/ijnpr.v13i2.51347
 
Language en
 
Relation Int. cl. (2021.01)- A61K 36/00, A61K 36/23, A61K 131/00, A61P 39/00
 
Publisher NIScPR-CSIR,India
 
Source IJNPR Vol.13(2) [June 2022]