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Amelioration of high levels of serum kidney function biomarkers by Vernonia amygdalina in monosodium glutamate induced rats

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Title Amelioration of high levels of serum kidney function biomarkers by Vernonia amygdalina in monosodium glutamate induced rats
 
Creator Onwubiko, Grace Nene
Nwankwo, Nicodemus Emeka
Egbuonu, Anthony Cemaluk Chinedum
Soribe, Blessing Amarachi
Okeke, Emmanuel Sunday
Eze, Chukwuemeka Joseph
 
Subject Ethanol extract
Kidney functionality
Minerals
Monosodium glutamate
Vernonia amygdalina
Vitamins
 
Description 197-205
Monosodium Glutamate (MSG), as a food seasoning agent, even at low doses, has been found to exert exceeding toxic
effect on the body system when used for a prolonged time. This study was aimed at investigating the effect of varying doses
of Vernonia amygdalina stem extract on MSG-induced alteration of some kidney function parameters in rats. Twenty (20)
adult male Albino rats (weighing 90-180 g), divided into five groups of four rats each, were used for the study. Some kidney
function parameters and histological examination of kidney tissues were determined according to standard methods. The
mineral and vitamin contents of V. amygdalina stem were also determined. In rats administered with MSG (8 mg/kg), there
were significant (P
 
Date 2022-08-11T05:54:43Z
2022-08-11T05:54:43Z
2022-06
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/60265
https://doi.org/10.56042/ijnpr.v13i2.36235
 
Language en
 
Relation Int. cl. (2021.01)- A61K 36/00, A61K 36/28, A61K 135/00, A61P 13/00
 
Publisher NIScPR-CSIR,India
 
Source IJNPR Vol.13(2) [June 2022]