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Antioxidant and antimicrobial potential of Canavalia gladiata (Jacq.) DC. leaves and seeds: GC-MS based metabolic profiling

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Title Antioxidant and antimicrobial potential of Canavalia gladiata (Jacq.) DC. leaves and seeds: GC-MS based metabolic profiling
 
Creator More, Kamlakar
Tayade, Sunil
Gawande, Prashant
Manik, Surendra
Shelke, Deepak
 
Subject Antimicrobial activity
Antioxidant
Bioactive compounds
Canavalia gladiata
GC-MS analysis
 
Description 163-169
Canavalia gladiata (Sword Bean; family Fabaceae) is a fast-growing climber crop that has been widely cultivated in
tropical and subtropical areas for its edible seeds and legumes. It has also been used as grain legume and medicinal plant in
China for thousands of years. The metabolites from leaves and seeds of C. gladiata were extracted in petroleum ether and
chloroform. Further, extracts were subjected to GC-MS analysis for metabolite profiling. Total of 31 phytoconstituents were
identified; 14 compounds were reported to have biological activities. The Tridecane reported from leaves and seeds
petroleum ether extract showed 10.67 and 2.72% of relative quantity of compound respectively and has antioxidant and
antimicrobial activity. Octasiloxane,1,1,3,3,5,5,7,7,9,9,11,11,11,15,15-hexadecamethyl (3.42%) found in petroleum ether
leaves extracts showed antimicrobial activity. Moreover, 1- Hexadecane constituted 10.23% in seeds and 3.71% relative
quantity in leaves extracted with chloroform showed antibacterial activity. The seeds and leaves extracted with chloroform
reported 1-Tetradecene in 6.59 and 6.03% relative quantity respectively has antifungal potential. While Phenol 2, 4-bis
[1, 1-dimethylethyl] reported in leaves (6.12%) and seeds (6.47%) chloroform extract act as antioxidant and antimicrobial
agents. The 1-Nonadecene in seeds (3.47%) and leaves (2.14%) chloroform extracts showed antifungal activity while
1-Docosene in seeds (2.98%) and leaves (1.71%) of chloroform extract showed antimicrobial potential. Nonadecane
constituted 3.06% in seeds and 2.78% in leaves chloroform extracts and has antioxidant potential. The present study
revealed that the leaves and seeds of C. gladiata are a good source of antioxidants and other biologically active ingredients.
However, petroleum ether and chloroform extracted different metabolites from seeds and leaves. Therefore, these findings
highlighted the importance of solvent in phytochemical extractions and further bioactivity of C. gladiata metabolites creates
an attention of researchers for their use in the field of paramedical industries and herbal medicine.
 
Date 2022-08-11T06:08:49Z
2022-08-11T06:08:49Z
2022-06
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscpr.res.in/handle/123456789/60270
https://doi.org/10.56042/ijnpr.v13i2.47499
 
Language en
 
Relation Int. cl. (2021.01)- A61K 36/00, A61K 36/48, A61K 127/00, A61K 131/00, A61P 31/00, A61P 39/00
 
Publisher NIScPR-CSIR,India
 
Source IJNPR Vol.13(2) [June 2022]