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<p>Effects of leaf extracts of selected medicinal plants on blood against hypotonic solution by measuring optical density: An <em>in vitro</em> study</p>

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Title Statement <p>Effects of leaf extracts of selected medicinal plants on blood against hypotonic solution by measuring optical density: An <em>in vitro</em> study</p>
 
Added Entry - Uncontrolled Name Yadav, Meena
Chaturvedi, Gargi
Jha, Neha
 
Uncontrolled Index Term Antidiabetic, Amla, Azadirachtaindica, CO-Hb, Hemolysis, Herbal, Holi basil, Homeostasis, Indian gooseberry, Neem, Ocimumtenuiflorum, oxy-Hb, Redox stress, Tulsi
 
Summary, etc. The medicinal plant leaf extracts alter the morphology of the cellular components of blood, especially RBCs. However, information on biochemical changes occurring during these events <em>in vitro</em> is lacking. Here, we studied the effect of medicinal plant [<em>Azadirachtaindica</em> A. Juss (Neem), <em>Emblica officinalis</em>Gaertn. (Indian Gooseberry or Amla) and <em>Ocimumtenuiflorum</em> L. (Holi basil or Tulsi)] leaf extracts as against the hypotonic solution by measuring the optical density of blood at various wavelengths at 0 and 30 min. the blood, exposed to hypotonic solution, showed cellular degradation and higher protein metabolism; higher glucose metabolism and oxidative cellular damage as well as higher oxygen absorption as compared to test samples. Among the three leaf extracts studied, the Amla extract treatment had comparatively more protective role for cellular components of the blood as against hypotonic solution. However, Tulsi extract significantly reduced hemolysis, heme catabolism and redox stress in RBCs. Tulsi also increased glucose metabolism indicating its antidiabetic property. To conclude, Amla leaf extract significantly reversed the effects of the hypotonic solution on the cellular components while Tulsi extract exhibited therapeutic role in maintaining homeostasis of cellular components in blood
 
Publication, Distribution, Etc. Indian Journal of Experimental Biology (IJEB)
2020-06-01 00:00:00
 
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http://op.niscair.res.in/index.php/IJEB/article/view/65508
 
Data Source Entry Indian Journal of Experimental Biology (IJEB); ##issue.vol## 58, ##issue.no## 06 (2020): IJEB [JUNE 2020]
 
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