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<strong>Synthesis of Bioactive Chlorinated </strong><strong>10<em>H</em>-Phenothiazines, Sulfones, Ribofuranosides and their Antimicrobial activity</strong>

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Title Statement <strong>Synthesis of Bioactive Chlorinated </strong><strong>10<em>H</em>-Phenothiazines, Sulfones, Ribofuranosides and their Antimicrobial activity</strong>
 
Added Entry - Uncontrolled Name Goyal, Arun ; Department of Chemistry, Govt P.G. College Rajgarh (Alwar), Rajasthan, 301408 Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan
Agarwal, Shikha ; Synthetic Organic Chemistry Laboratory, Department of Chemistry, MLSU, Udaipur
Gautam, D C; Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan
 
Uncontrolled Index Term Phenothiazine, Smiles rearrangement, Sulfones, Antimicrobial properties, Ribofuranosides.
 
Summary, etc. Heterocyclic Chemistry is a vast thrust area for researchers. Various publications on biologically active phenothiazines and their ribofuranosides in recent years have aroused the interest of scientists in the synthesis and biological activity of these heterocycles. This article reports synthesis of some new prospective bioactive 10<em>H-</em>phenothiazines, their sulfones and ribofuranosides that have shown significant antimicrobial activity against some selected strains of fungi, Gram positive and gram negative bacteria and lead us to develop a possibly potent class of antimicrobial agents. 10<em>H</em>-phenothiazines were prepared via Smiles rearrangement. Their sulfones and ribofuranosides were prepared by oxidation with 30% hydrogen peroxide in glacial acetic acid and reaction with b-D-ribofuranose-1-acetate-2,3,5-tribenzoate (sugar) respectively.
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-08-16 12:31:01
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJC/article/view/65044
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 8 (2022): Indian Journal of Chemistry - (IJC)
 
Language Note en