Anti-tyrosinase, anti-elastase, and antioxidant activities of some symmetric bisthiocarbohydrazone compounds
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Title |
Anti-tyrosinase, anti-elastase, and antioxidant activities of some symmetric bisthiocarbohydrazone compounds
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Creator |
Kaya, Yeliz
Sacan, Ozlem Erçağ, Ayşe Yanardag, Refiye |
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Subject |
Thiocarbohydrazone
isatin antityrosinase antielastase antioxidant |
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Description |
895-900
Symmetric bisthiocarbohydrazone compounds (1, 2, 3) were obtained by the condensation of thiocarbohydrazide with carbonyl compounds such as isatin (a heterocyclic ketone) and two hydroxyl aldehydes (2-hydroxybenzaldehyde, 2-hydroxy-1- naphthaldehyde) respectively, according to the previously reported methods. These synthesized compounds were evaluated in terms of their anti-tyrosinase, anti-elastase and antioxidant potentials in vitro. All of the tested compounds exhibited antityrosinase and anti-elastase activities. It was observed that the inhibition increased with the increase of bisthiocarbohydrazone concentrations. Compound 1 showed the highest anti-tyrosinase activity. The anti-tyrosinase activity is decreasing in the following order; 2 |
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Date |
2022-08-16T08:33:00Z
2022-08-16T08:33:00Z 2022-08 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60294 https://doi.org/10.56042/ijc.v61i8.59458 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJC Vol.61(08) [AUG 2022]
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