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Synthesis of bioactive chlorinated 10H-phenothiazines, sulfones, ribofuranosides and their antimicrobial activity

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Title Synthesis of bioactive chlorinated 10H-phenothiazines, sulfones, ribofuranosides and their antimicrobial activity
 
Creator Goyal, Arun
Agarwal, Shikha
Gautam, D C
 
Subject Phenothiazine
Smiles rearrangement
Sulfones
Antimicrobial properties
Ribofuranosides
 
Description 842-848
This article reports synthesis of some new prospective bioactive 10H-phenothiazines, their sulfones and ribofuranosides
that have shown significant antimicrobial activity against some selected strains of fungi, gram positive and gram negative
bacteria and leads us to develop a possibly potent class of antimicrobial agents. 10H-phenothiazines are prepared via Smiles
rearrangement. Their sulfones and ribofuranosides are prepared by oxidation with 30% hydrogen peroxide in glacial acetic
acid and reaction with -D-ribofuranose-1-acetate-2,3,5-tribenzoate (sugar), respectively.
 
Date 2022-08-16T08:52:52Z
2022-08-16T08:52:52Z
2022-08
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60300
https://doi.org/10.56042/ijc.v61i8.65044
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.61(08) [AUG 2022]