Total serum cholesterol level in patients with major depressive disorder: Simple yet undermined
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Title |
Total serum cholesterol level in patients with major depressive disorder: Simple yet undermined
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Creator |
TK, Madhura
Farheen, Fatima Pandurangi, Aditya Jaalam, Kamaruddin M, Mahesh |
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Subject |
Anti-depressants
Major depressive disorder (MDD) Neuro-inflammation Serotonin Serum cholesterol level Synapse |
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Description |
836-842
Human brain cholesterol acts as structural components of cellular membrane, synapse and dendrite formation. Researchers have found a possible association between low serum cholesterol levels and mood disorders though the literature from India in this regard is limited. To estimate serum levels of total cholesterol in patients with major depressive disorder. 75 patients of MDD were compared with equal number of age and sex matched controls. 5 ml of fasting sample of blood was obtained in a plain vacutainer to analyse total cholesterol level by Cholesterol oxidase-peroxidase method. Statistical analysis: The obtained results were tabulated and analyzed by multiple logistic regression analysis, independent ttest, Chi-square test and area under the curve. The mean level of cholesterol in cases (158.85±61.22 mg/dL) which was significantly lower compared to the controls (182.71±40.98 mg/dL) with P |
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Date |
2022-08-23T11:14:26Z
2022-08-23T11:14:26Z 2022-08 |
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Type |
Article
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Identifier |
0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscpr.res.in/handle/123456789/60341 https://doi.org/10.56042/ijbb.v59i8.65426 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJBB Vol.59(8) [AUGUST 2022]
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