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Total serum cholesterol level in patients with major depressive disorder: Simple yet undermined

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Title Total serum cholesterol level in patients with major depressive disorder: Simple yet undermined
 
Creator TK, Madhura
Farheen, Fatima
Pandurangi, Aditya
Jaalam, Kamaruddin
M, Mahesh
 
Subject Anti-depressants
Major depressive disorder (MDD)
Neuro-inflammation
Serotonin
Serum cholesterol level
Synapse
 
Description 836-842
Human brain cholesterol acts as structural components of cellular membrane, synapse and dendrite formation.
Researchers have found a possible association between low serum cholesterol levels and mood disorders though the
literature from India in this regard is limited. To estimate serum levels of total cholesterol in patients with major depressive
disorder. 75 patients of MDD were compared with equal number of age and sex matched controls. 5 ml of fasting sample of
blood was obtained in a plain vacutainer to analyse total cholesterol level by Cholesterol oxidase-peroxidase method.
Statistical analysis: The obtained results were tabulated and analyzed by multiple logistic regression analysis, independent ttest,
Chi-square test and area under the curve. The mean level of cholesterol in cases (158.85±61.22 mg/dL) which was
significantly lower compared to the controls (182.71±40.98 mg/dL) with P
 
Date 2022-08-23T11:14:26Z
2022-08-23T11:14:26Z
2022-08
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscpr.res.in/handle/123456789/60341
https://doi.org/10.56042/ijbb.v59i8.65426
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJBB Vol.59(8) [AUGUST 2022]