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Antimicrobial and toxicity properties of crystalline potassium tetrachlorocuprate (II) dehydrate

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Field Value
 
Title Antimicrobial and toxicity properties of crystalline potassium tetrachlorocuprate (II) dehydrate
 
Creator Pavithra, M
Raj, MB Jessie
 
Subject Mitscherlichite
FT-IR
Microbial control and cell viability
XRD
 
Description 813-822
In the current scenario, microbial infections are major concern and they multiply so rapidly throughout the world; also, they
cause serious bio illness and can even results in death among humans. Complexes framed by crystalline metal ions have been used
as medications, because of a wide range of organic activities against harmful microorganisms. In the present study, greenish blue
potassium tetrachlorocuprate (II) dihydrate K2CuCl4.2H2O crystalline precipitates were prepared by solvent evaporation method at
ambient temperature. This complex was found in nature as a rare mineral Mitscherlichite. For finding the crystalline parameters of
the sample, a Single-crystal XRD analysis was used and the data confirms. K2CuCl4.2H2O crystallizes into a tetragonal structure.
The formation of bonds and the presence of functional groups in the complex were determined from Surface morphology studies,
the very clear morphology of the complex has smoothing surface, defect-free, small microstructures and stacklike shapes of a welldefined
crystalline pattern. Also, addition, optical analysis supports that its possibility in antimicrobial applications. The sample
shows comparatively good results in positive control of antibacterial and antifungal activities, namely Gentamicin,
Chloramphenicol and Clotrimazole. IC50 and optical density (OD) values were used to determine the cytotoxicity and cell viability,
respectively. In vitro cytotoxicity of MTT assay shows in graphical abstract.
 
Date 2022-08-23T11:20:08Z
2022-08-23T11:20:08Z
2022-08
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscpr.res.in/handle/123456789/60343
https://doi.org/10.56042/ijbb.v59i8.46912
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJBB Vol.59(8) [AUGUST 2022]