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<p class="Articletitle"><span lang="EN-GB">A convenient and eco-friendly one-pot synthesis of 3-triazolyl-2-iminochromenes and investigation of their antioxidant properties</span></p><br />

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Title Statement <p class="Articletitle"><span lang="EN-GB">A convenient and eco-friendly one-pot synthesis of 3-triazolyl-2-iminochromenes and investigation of their antioxidant properties</span></p><br />
 
Added Entry - Uncontrolled Name Basha, Khadhar Navaz Umar; Sona – Centre for Advanced Research in Organic Materials (Sona AROMA), Department of Chemistry, Sona College of Technology, Salem 636 005, Tamil Nadu, India
Gnanamani, Shanthi ; Sona – Centre for Advanced Research in Organic Materials (Sona AROMA), Department of Chemistry, Sona College of Technology, Salem 636 005, Tamil Nadu, India
Shanmugam, Prakash ; Department of Chemistry, Periyar University, Periyar Palkalai Nagar, Salem 636 011, Tamil Nadu, India
Venugopal, Sujatha ; Department of Chemistry, Periyar University, Periyar Palkalai Nagar, Salem 636 011, Tamil Nadu, India
 
Uncontrolled Index Term Multicomponent reaction, 2-azido acetonitrile, salicylaldehyde, phenylacetylene, CuI/K2CO3, chromenes
 
Summary, etc. <p class="Abstract">A simple, green and efficient procedure for the synthesis of highly functionalized 3-triazolyl-2-iminochromenes by using a one-pot three component reaction of 2-azido acetonitrile, phenylacetylene and salicylaldehyde in water using CuI/K<sub>2</sub>CO<sub>3</sub> is described. The present protocol offers advantages like high atom economy, simple methodology, shorter reaction time, easy product isolation, no chromatographic purification and avoidance of environmentally hazardous solvents. Compounds <strong>4a-d</strong>,<strong> 4g-h</strong> and <strong>6a-b</strong> have been investigated for antioxidant activity. Compound <strong>4c</strong> is found to be the most active among the series showing high reducing power and free radical scavenging activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-09-20 12:49:50
 
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http://op.niscair.res.in/index.php/IJC/article/view/66344
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 9 (2022): Indian Journal of Chemistry-(IJC)
 
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