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<strong>In vitro anti-oxidant and In-vitro anti-diabetic studies of silver, gold and copper nanoparticles synthesized using the flowers of Azhadirachta indica</strong>

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Title Statement <strong>In vitro anti-oxidant and In-vitro anti-diabetic studies of silver, gold and copper nanoparticles synthesized using the flowers of Azhadirachta indica</strong>
 
Added Entry - Uncontrolled Name Gopalakrishnan, V ; Department of Chemistry, Ramakrishna Mission Vivekananda College, Chennai 600 004, India
Muniraj, S ; Department of Chemistry, Ramakrishna Mission Vivekananda College, Chennai 600 004, India
 
Uncontrolled Index Term Anti-diabetic; Anti-oxidant; Metal nanoparticles; Neem flower; A Indica
 
Summary, etc. <p><span>Nanotechnology industry focuses primarily on promoting nanoscience as a “green” technology to provide a way for less-toxic environmentally benign economic expansion and to synthesize eco- friendly and innocuous drugs to cater to the needs of the contemporary world. An attempt has been made to prepare silver, gold and copper nanoparticles using the aqueous flower extract of Azhadiracta indica (neem). In-vitro anti-oxidant efficacy of these metal nanoparticles (NPs) were investigated through i) Hydrogen atom transfer (HAT) reaction based assays- (ABTS scavenging effect and Hydroxyl radical scavenging effect) and ii) Electron transfer (ET) reaction based assays(DPPH radical scavenging activity and NO free radical scavenging activity). CuNPs exhibits better activity compared to AgNPs and AuNPs. In vitro anti-diabetic test was conducted for all the three NPs through three methods namely inhibition of α- glucosidase enzyme assay, inhibition of alpha amylase enzyme assay and Non-enzymatic glycosylation of hemoglobin assay. CuNPs had a remarkable anti-diabetic activity which was close to the standard acarbose.</span></p>
 
Publication, Distribution, Etc. Indian Journal of Chemical Technology (IJCT)
2022-10-19 15:20:58
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJCT/article/view/67633
 
Data Source Entry Indian Journal of Chemical Technology (IJCT); ##issue.vol## 28, ##issue.no## 5 (2021): Indian Journal of Chemical Technology
 
Language Note en