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<p>An efficient sodium chloride-catalyzed synthesis of bis(indolyl) methanes in green solvent and their antibacterial evaluation</p>

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Title Statement <p>An efficient sodium chloride-catalyzed synthesis of bis(indolyl) methanes in green solvent and their antibacterial evaluation</p>
 
Added Entry - Uncontrolled Name Longkumer, Lensayula ; Department of Chemistry, Nagaland University, Lumami 798 627, Nagaland, India
Imchen, Putusenla ; Department of Chemistry, Nagaland University, Lumami 798 627, Nagaland, India
Zhimomi, Betokali K; Department of Chemistry, Nagaland University, Lumami 798 627, Nagaland, India
Swu, Toka ; Department of Chemistry, Pondicherry University, Kalapet, Puducherry 605 014, India
Phucho, I Tovishe ; Department of Chemistry, Nagaland University, Lumami 798 627, Nagaland, India
 
Uncontrolled Index Term Bis(indolyl)methanes, aldehydes, NaCl, aqueous medium, antibacterial
 
Summary, etc. <p style="text-align: justify;">A series of bis(indolyl)methanes derivatives have been synthesized using an efficient sodium chloride-catalyst in aqueous medium. Herein, substituted aldehydes have been successfully condensed with indole in an aqueous medium. Sodium chloride serves as an efficient and green catalyst as it is freely available and environmentally benign. Water used as green solvent also has no negative impact on the environment. The experiment follows a simple reaction procedure and completion of the reaction is achieved within 3-4 hours. The synthesized compounds have also been evaluated for their <em>in vitro </em>antibacterial property using 4 strains of bacteria, namely <em>Bacillus subtilis</em>,<em> Staphylococcus aureus</em>,<em> Escherichia coli </em>and<em> Klebsiella pneumonia</em> where Streptomycin is used as the reference standard.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-10-21 16:51:33
 
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http://op.niscair.res.in/index.php/IJC/article/view/67208
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 10 (2022): Indian Journal of Chemistry-(IJC)
 
Language Note en