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<p><strong>One-pot Michael addition and cyclo-elimination cascade synthesis </strong><strong>of thiazolo-[ 4,5- <em>b</em>]pyridin- 6-carbonitrile  scaffold</strong></p>

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Title Statement <p><strong>One-pot Michael addition and cyclo-elimination cascade synthesis </strong><strong>of thiazolo-[ 4,5- <em>b</em>]pyridin- 6-carbonitrile  scaffold</strong></p>
 
Added Entry - Uncontrolled Name Tiwari, Shailendra ; University of Allahabad
Singh, Vishal Kumar
Ahmad, Akeel
Begum, Kahkashan
Department of Chemistry, University of Allahabad
 
Uncontrolled Index Term Organic Chemistry; Antimicrobial studies
3-Benzyl-4-thiazolidinon-2-thione; carbonitrile; antibacterial; antifungal activity
 
Summary, etc. <p>A series of thiazolo [4,5-<em>b</em>]- pyridine-6-carbonitriles scaffold have been synthesized conveniently and smoothly in a single step in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds <strong>3c</strong>, <strong>3d</strong>, <strong>3e</strong>, <strong>3f</strong>, <strong>4c</strong>, <strong>4d</strong>, <strong>4e</strong> and <strong>4f</strong> have shown good antibacterial as well as antifungal activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry (IJC)
2022-10-21 16:51:33
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJC/article/view/59435
 
Data Source Entry Indian Journal of Chemistry (IJC); ##issue.vol## 61, ##issue.no## 10 (2022): Indian Journal of Chemistry-(IJC)
 
Language Note en