One-pot Michael addition and cyclo-elimination cascade synthesis of thiazolo-[4,5-b]pyridin-6-carbonitrile scaffold
NOPR - NISCAIR Online Periodicals Repository
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Title |
One-pot Michael addition and cyclo-elimination cascade synthesis of thiazolo-[4,5-b]pyridin-6-carbonitrile scaffold
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Creator |
Tiwari, Shailendra
Singh, Vishal Kumar Rahmani, Shahla Ahmad, Akeel Begum, Kahkashan |
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Subject |
3-Benzyl-4-thiazolidinon-2-thione
Carbonitrile Antibacterial antifungal activity |
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Description |
1097-1102
A series of thiazolo [4,5-b]- pyridine-6-carbonitriles scaffold have been synthesized conveniently and smoothly in a single step in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds 3c, 3d, 3e, 3f, 4c, 4d, 4e and 4f have shown good antibacterial as well as antifungal activity. |
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Date |
2022-10-21T04:51:56Z
2022-10-21T04:51:56Z 2022-10 |
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Type |
Article
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Identifier |
2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/60720 https://doi.org/10.56042/ijc.v61i10.59435 |
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Language |
en
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Publisher |
NIScPR-CSIR,India
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Source |
IJC Vol.61(10) [Oct 2022]
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