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<p>Anticancer Potentials of Zinc Oxide Nanoparticles against Liver and Breast Cancer Cell Lines</p>

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Title Statement <p>Anticancer Potentials of Zinc Oxide Nanoparticles against Liver and Breast Cancer Cell Lines</p>
 
Added Entry - Uncontrolled Name Elsayed, E A; Bioproducts Research Chair, Zoology Department, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia Natural and Microbial Products Department, National Research Centre, Dokki, Cairo 12622, Egypt
Moussa, S A; Biophysics Group, Biochemistry Department, National Research Centre, Dokki 12622, Giza, Egypt
El-Enshasy, H A; Institute of Bioproduct Development, Universiti Teknologi, Malasiya 81310, skudai Johor, Malasiya
Wadaan, M A; Bioproducts Research Chair, Zoology Department, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
 
Uncontrolled Index Term Cancer cells; In vitro; Nano-biotechnology; Zinc oxide nano-particles 
 
Summary, etc. <p class="Abstract"><span lang="EN-GB">The aim of the present study was to evaluate the <em>in vitro</em> cytotoxic effects of zinc oxide nanoparticles (ZnONPs) with particle size of 40 and 50 nm against human hepatocellular carcinoma and human breast cancer cell lines. The effects of nanoparticles were analyzed after 24 hours of incubation using standard MTT assay. Incubation of ZnONPs with different cells produced a dose-dependent inhibition of cell growth. The IC<sub>50</sub> values of ZnONPs for both prepared samples (40 and 50 nm) were comparable. It has been noticed that MCF-7 and MDA cells were more affected by the prepared 50 nm than the 40 nm ZnONPs. On the other hand, HepG2 cells showed inverse relation in terms of their response to the size of the prepared NPs.</span></p><br />
 
Publication, Distribution, Etc. Journal of Scientific & Industrial Research
2022-11-09 07:52:48
 
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http://op.niscair.res.in/index.php/JSIR/article/view/68140
 
Data Source Entry Journal of Scientific & Industrial Research; ##issue.vol## 79, ##issue.no## 1 (2020): Journal of Scientific & Industrial Research
 
Language Note en