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Synthesis and characterization of graphene nanosheets for electrochemical quantification of chlorpheniramine maleate drugs using a modified glassy carbon electrode

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Title Synthesis and characterization of graphene nanosheets for electrochemical quantification of chlorpheniramine maleate drugs using a modified glassy carbon electrode
 
Creator Murugan, E
Poongan, A
Kesava, M
Vinitha, A
 
Subject Chlorpheniramine maleate
Electrochemical sensor
Graphene@GCE
Ullman method
 
Description 713-720
The development of innovative sensors for the detection of analytes at extremely low concentrations with great sensitivity and selectivity has been a major focus of this study. The electrochemical activity of chlorpheniramine maleate (CPRM) in the presence of a graphene modified GCE has been investigated. Cyclic voltammograms (CV) have been obtained in the linear dynamic range 3.5- 156 μM while the optimum pH range and the maximum peak current (IPa) have been measured at pH 7.3. The process on the electrode's surface, diffusion regulated, heterogeneous rate constant, charge transfer coefficient, and the number of electrons transferred among the physicochemical properties have been obtained. Differential pulse voltammetry (DPV) of CPRM at the modified has electrode revealed a good linear calibration curve with a linear range of 10 to 60 μM and limit of detection of 0.062 μM. The suggested sensor has been fabricated and utilized to determine CPRM in medicines as well as serum samples.
 
Date 2022-11-21T11:18:12Z
2022-11-21T11:18:12Z
2022-11
 
Type Article
 
Identifier 0975-0991 (Online); 0971-457X (Print)
http://nopr.niscpr.res.in/handle/123456789/60870
https://doi.org/10.56042/ijct.v29i6.67423
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJCT Vol.29(6) [November 2022]