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Evaluation of biochemical and antioxidant properties of crude extracts from the Indian cattle leech Poecilobdella granulosa

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Title Evaluation of biochemical and antioxidant properties of crude extracts from the Indian cattle leech Poecilobdella granulosa
 
Creator Padmanaban, D
Muthusamy, R G
Sahayanathan, G J
Raja, K
Chinnasamy, A
 
Subject 2, 2-diphenyl-1-picrylhydrazyl
Antioxidant
Free radical
Poecilobdella granulosa
Saliva
Superoxide
 
Description 688-693
Oxidative stress is one of the factors influencing the structure and function of cells, tissues, and their components.
Natural antioxidants have emerged as prophylactic and therapeutic agents for diseases like cancer and cardiovascular
disease. The objective of the current study is to assess the biochemical composition and antioxidant potential of crude
extracts from various organs of the Indian cattle leech Poecilobdella granulosa. The biochemical constituents and protein
profiles of various crude samples were determined by Native and SDS polyacrylamide gel electrophoresis. Moreover, four
different crude samples were subjected to check free radical scavenging activity. In the biochemical analysis, protein and
carbohydrate content were found to be higher in whole-body extract and several major and minor bands were found ranging
from 22 to 110 kDa during qualitative analysis. Interestingly, among the four crude samples, saliva alone showed
antioxidant activity by 2,2-diphenyl-1-picrylhydrazyl and superoxide anion radical scavenging activity. This study
concluded that the crude saliva extract from P. granulosa is a highly selective and effective antioxidant for human welfare.
 
Date 2022-11-24T05:46:28Z
2022-11-24T05:46:28Z
2022-11
 
Type Article
 
Identifier 2582-6727 (Online); 2582-6506 (Print)
http://nopr.niscpr.res.in/handle/123456789/60913
https://doi.org/10.56042/ijms.v51i08.40854
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJMS Vol.51(08) [August 2022]