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Synthesis and biological activities of 3,6-disubstituted-1,2,4-triazolo(3,4-b)-1,3, 4-thiadiazoles

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Title Synthesis and biological activities of 3,6-disubstituted-1,2,4-triazolo(3,4-b)-1,3, 4-thiadiazoles
 
Creator Prasad, Subedar
Pandey, Avanish Kumar
Kumar, Dhirendra
Prasad, Akhilesh
Gupta, Chitrasen
 
Subject Triazoles
Triazolo thiadiazoles
Pharmacological activities
 
Description 1288-1294
4-Amino-5aryl/heteroaryl substituted 3-mercapto-1,2,4-triazoles, have been prepared from the corresponding aromatic
carboxylic acid through a multistep sequence. These trizoles have been made to react with various aromatic acids to yield
3,6-disubstituted-1,2,4-triazole{3,4-b}-1,3,4 thiadiazoles. Elemental analysis IR, 1H NMR and mass spectral data has
elucidated the structures of all newly synthesized compounds. These compounds have shown significant pharmacological
activities and are found to be highly active against various fungi and bacteria.
 
Date 2022-12-15T05:42:03Z
2022-12-15T05:42:03Z
2022-12
 
Type Article
 
Identifier 2583-1321 (Online); 0019-5103 (Print)
http://nopr.niscpr.res.in/handle/123456789/61015
https://doi.org/10.56042/ijc.v61i12.69476
 
Language en
 
Publisher NIScPR-CSIR,India
 
Source IJC Vol.61(12) [Dec 2022]