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Computational approaches and challenges for identification and annotation of non-coding RNAs using RNA-Seq

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Computational approaches and challenges for identification and annotation of non-coding RNAs using RNA-Seq
 
Creator Dindhoria, Kiran
Monga, Isha
Thind, Amarinder Singh
 
Subject QR Microbiology
 
Description Significant innovations in next-generation sequencing techniques and bioinformatics tools have impacted our appreciation and understanding of RNA. Practical RNASeq applications have evolved in conjunction with sequence technology and bioinformatic tool advances. In this review, we explained various computational resources, tools, and bioinformatics analyses advancement for small and large non-coding RNAs. These include non-coding RNAs (ncRNAs) such as piwi, micro, circular, and long ncRNAs. In addition, this article discusses future challenges, single-cell level sequencing for non-coding RNAs, and advantages of using long-read sequencing to annotate lncRNAs.
 
Publisher Springer
 
Date 2022-11-21
 
Type Article
PeerReviewed
 
Relation https://link.springer.com/article/10.1007/s10142-022-00915-y
http://crdd.osdd.net/open/3039/
 
Identifier Dindhoria, Kiran and Monga, Isha and Thind, Amarinder Singh (2022) Computational approaches and challenges for identification and annotation of non-coding RNAs using RNA-Seq. FUNCTIONAL & INTEGRATIVE GENOMICS, 22 (6). pp. 1105-1112.