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Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus

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Title Antidoting Effect of Vitamin K1 Supplementation on Difethialone Poisoned House Rat, Rattus rattus Linneaus
Not Available
 
Creator V. Chaudhary
R. S. Tripathi
 
Subject Rattus rattus, Anticoagulants, Difethialone, Baits, Vitamin K1 supplemented food, Plain Food.
 
Description Not Available
With the advent of second-generation anticoagulant rodenticides rodent management technology has substantially improved, since they provide sustainable control of rodents and are relatively safe to non-targets than the acute rodenticides. Due to their anticoagulant nature vitamin K1 regarded as an effective antidote for such rodenticides, Two dosages (1 and 2 mg/kg) of vitamin K1 supplementation for 5 and 15 days were given to house rat R. rattus fed on difethialone bait (0.0025%) for one day for studying the effect of antidoting on poisoned rats. The results indicated that the lower dosage could not reverse the anticoagulation process, however the period of mortality was considerably increased from 3-9 days (in control) to 4-11 and 11-22 days (5 and 15 days supplementation regime, respectively). However, when the vitamin K1 dosage was doubled and given for 15 days, antidoting was more pronounced due to reversal of anticoagulation process in 83% cases as five of the six rats became normal within a month of difethialone poisoning.
Not Available
 
Date 2019-04-26T06:27:06Z
2019-04-26T06:27:06Z
2006-01-01
 
Type Research Paper
 
Identifier Not Available
0570-1791
http://krishi.icar.gov.in/jspui/handle/123456789/18959
 
Language English
 
Relation Not Available;
 
Publisher Arid Zone Research Association of India