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Cloning and phylogenetic analysis of Interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) from Indian dromedaries (Camelus dromedarius)

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Title Cloning and phylogenetic analysis of Interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) from Indian dromedaries (Camelus dromedarius)
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Creator G. Nagarajan
Shelesh Kumar Swamia
S.K. Ghoruia
K.M.L. Pathak
R.K. Singh
N.V. Patil
 
Subject Dromedarian
Camel
Cytokine
Phylogenetic
genes
 
Description Not Available
The cDNAs of two proinflammatory cytokines viz., IL-6 and TNF- from dromedarian
camels were amplified by PCR using bactrian camel sequences and subsequently cloned
for sequence analysis. Relationship based on amino acid revealed that dromedarian camel
IL-6 shared 99.5% identity both at nucleotide and amino acid level with bactrian camel IL-6
and in case of TNF- , the identity of dromedarian camel was 99.4% and 99.1% at nucleotide
and amino acid level, respectively with that of bactrian camel. Phylogenetic analysis based
on their amino acid sequences indicated the close relationship in these cytokine genes
between dromedarian camel and other members of camelids.
Not Available
 
Date 2020-08-21T10:37:44Z
2020-08-21T10:37:44Z
2011-01-28
 
Type Research Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/39929
 
Language English
 
Relation Not Available;
 
Publisher Elsevier