Record Details

Effect of Solvents and Extraction Methods on Forskolin Content from Coleus forskholii Roots

KRISHI: Publication and Data Inventory Repository

View Archive Info
 
 
Field Value
 
Title Effect of Solvents and Extraction Methods on Forskolin Content from Coleus forskholii Roots
Not Available
 
Creator Pritee Singh and M. A. Suryanarayana
 
Subject Coleus forskohlii, extraction method, extraction solvent, forskolin
 
Description Not Available
Coleus forskohlii roots are mainly used for extraction of the bioactive diterpenoid, forskolin, which has
enormous biological activities. In this study, impact of the solvent and extraction method on forskolin
content from Coleus forskohlii root powder was investigated. Nine solvents from different polarity
group were tested for forskolin extraction. It was found that the efficiency of the solvents used to extract
forskolin varied considerably (0.18 to 2.91 %). The average values indicated that among all the extractives,
forskolin content was significantly higher in methanol (2.91 %), followed by ethanol (2.59 %), and least
content was found in water (0.18 %). Low polarity solvents were not found very effective for forskolin
extraction. Further three different extraction methods (Soxhlet/refluxing, ultrasound and microwaveassisted
solvent extraction) were also compared using safest and most effective solvent for forskolin yield.
As ethanol exhibited good extraction efficiency for forskolin and is a safe solvent, it was chosen for further
optimization of extraction method. Soxhlet extraction technique gave higher yield of forskolin (0.17 to
2.83 %) compared to microwave-assisted solvent extraction (0.09 to 2.29 %) and ultra sound-assisted
extraction (0.08 to 1.47 %). From these results it was evident that the extraction of forskolin depended on
extraction process as well as the solvent used.
Not Available
 
Date 2020-02-26T03:38:49Z
2020-02-26T03:38:49Z
2019-12-01
 
Type Article
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/33114
 
Language English
 
Relation Not Available;
 
Publisher Not Available