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Comparative investigation of cellular response of nanoparticles

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Title Comparative investigation of cellular response of nanoparticles
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Creator Sandeep Kumar
Gaurav Bhanjana
Neeraj Dilbaghi
Anju Manuja
 
Subject Zirconium oxide nanoparticles; iron oxide nanoparticles; titanium oxide nanoparticles; aluminum oxide nanoparticles; resazurin sodium.
 
Description Not Available
Nanoparticles are being designed with chemically modifiable surfaces to attach a variety of molecules to improve biosensing,
imaging techniques, delivery vehicles, and other useful biological tools. Keeping this in view, the present research work is
focused on investigation of cytotoxicity of metal oxide nanoparticles. Different metal oxide nanoparticles (e.g titanium
dioxide, zinc oxide, iron oxide, aluminum oxide etc) of different sizes and different concentrations were used to investigate
the cellular response. Electron microscopy and colorimetric assays were used to characterize the various process steps.
Zirconium oxide nanoparticles were used in suspension form stabilized with stabilizer and the others were used as their
aqueous suspension. Results clearly reflect that as the concentration increases, cytotoxicity also increases. As aggregation
occurs, cytotoxicity decreases. In suspension with stabilizer, cytotoxicity is more as compared to aqueous suspensions.
Copyright © 2012 VBRI Press.
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Date 2021-07-15T10:20:19Z
2021-07-15T10:20:19Z
2012-06-26
 
Type Article
 
Identifier 22
0976-3961
http://krishi.icar.gov.in/jspui/handle/123456789/48247
 
Language English
 
Relation Not Available;
 
Publisher Not Available