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PCR –RFLP analysis of HA and NA genes of a H5N1 isolate being a possible escape mutant

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Title PCR –RFLP analysis of HA and NA genes of a H5N1 isolate being a possible escape mutant
Not Available
 
Creator Bhardwaj P
Sridevi R
Shanmugasundaram N
Murugkar HV
Dubey SC
Jain R
Prakash A
 
Subject Avian influenza(AIV)
H5N1
PCR -RFLP
HA
NA
 
Description Not Available
New AIV strain continue to emerge because of genetic instability of influenza virus and lack of
proof reading and repair mechanism makes AIV genome easily prone to error that occur during
replication. This study provide an update of H5N1 being an escape mutant which escaped from a
immunized bird in aimmunization experiment conducted on birds with virus strain
A/Duck/Tripura/103597/2008(H5N1). This article provide an update of H5N1 virus as it was
evolving, creating the potential for new strain that is efficiently transmitted from birds to birds,
birds to human or human to human remains highly lethal. The emergence of escape mutant may
be either because of antigenic drift or genetic shift which results in H5N1 variants.
Not Available
 
Date 2018-11-03T04:41:11Z
2018-11-03T04:41:11Z
2015-07-19
 
Type Research Paper
 
Identifier Not Available
2319-5983
http://krishi.icar.gov.in/jspui/handle/123456789/9135
 
Language English
 
Relation Not Available;
 
Publisher JERAD Publications