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Comprehensive review on recent developments in the diagnostics and vaccines against peste des petits ruminants

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Title Comprehensive review on recent developments in the diagnostics and vaccines against peste des petits ruminants
Not Available
 
Creator Gomes AR
Veeregowda BM
Byregowda SM
Balamurugan V
 
Subject PPR
Diagnostics
Vaccines
Recombinant technology
Reverse genetics
 
Description Not Available
Peste des petits ruminants (PPR), a viral disease of goats and sheep caused by a morbillivirus of the family paramyxoviridae is a major threat to small ruminant farming. Global announcement of PPR eradication by 2030 has opened lot of research gaps for the development of vaccines and diagnostics for differentiating infected and vaccinated animals. With the advent of recombinant DNA technology, recombinant protein based vaccines and/or diagnostics are being tested in various heterologous systems across the globe for development of vaccines and/or diagnostic antigens. The recombinant viral proteins, virus like particle based vaccines, bivalent/multivalent vaccines, recombinant viral vectored vaccines, RNA interference as a therapy, suicidal DNAs, synthetic epitopes and peptides, reverse genetics, anti idiotypic antibody based vaccines and helper cell dependent diagnostics represent the present vaccine/diagnostic development strategies for the effective control and eradication of PPR. This review comprehend the current scenario of recombinant technology based vaccines and diagnostics, virus like particles (VLPs), reverse genetics approach etc., in the development of diagnostics and vaccines against PPR.
Not Available
 
Date 2018-11-06T03:35:32Z
2018-11-06T03:35:32Z
2016-06-30
 
Type Research Paper
 
Identifier Not Available
2055-6128
http://krishi.icar.gov.in/jspui/handle/123456789/9424
 
Language English
 
Relation Not Available;
 
Publisher Smith and Franklin Academic Publishing corporation