Effect of dietary supplementation of Eclipta alba on oxidative stress and liver damage induced by aflatoxin in broilers
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Title |
Effect of dietary supplementation of Eclipta alba on oxidative stress and liver damage induced by aflatoxin in broilers
Not Available |
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Creator |
Umaya RS
Manpal S Krishnamoorthy P Sejian V David ICG |
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Subject |
Aflatoxin B1
Broilers Eclipta alba Liver damage Oxidative stress |
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Description |
Not Available
The primary aim of the present study was to evaluate the efficacy of Eclipta alba leaf powder to ameliorate the oxidative stress and liver damage induced by aflatoxin B1 (AFB1) in broilers. Day-old male broilers were fed with basal diet (control), basal diet supplemented with E. alba (1.0%), basal diet with 1.0 ppm AFB1 or AFB1 (1.0 ppm) with E. alba (1.0%) for 42 days. Birds fed AFB1 showed significantly higher serum AST and ALT activities, and decreased concentrations of total protein, cholesterol and albumin. AFB1 feeding significantly increased hepatic lipid peroxidation products, decreased antioxidant enzymes and induced pathological changes in liver. The supplementation of E. alba leaf powder with AFB1 contaminated diet significantly improved serum biochemical profile, reduced the oxidative stress and pathological changes in liver. The present study revealed that supplementation of E. alba reduces the liver damage and oxidative stress induced by AFB1 and offer protection against aflatoxin toxicity in broilers. Not Available |
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Date |
2019-02-04T04:43:54Z
2019-02-04T04:43:54Z 2018-05-31 |
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Type |
Research Paper
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Identifier |
Not Available
0367-8318 http://krishi.icar.gov.in/jspui/handle/123456789/16704 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Indian Council of Agricultural Research
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