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Antiviral activity of crude extracts of Eugenia jambolana Lam. against Highly pathogenic avian influenza (H5N1) virus

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Title Antiviral activity of crude extracts of Eugenia jambolana Lam. against Highly pathogenic avian influenza (H5N1) virus
Not Available
 
Creator Sood, R.
Swarup, D.
Bhatia, S.
Kulkarni, D.D.
Dey, S.
Saini, M.
Dubey, S. C.
 
Subject Antiviral activity of crude extracts of Eugenia jambolana Lam
Avian influenza (H5N1) virus
India
 
Description Not Available
Crude extracts of leaves and bark of E. jambolana were tested for antiviral activity against highly pathogenic avian influenza virus (H5N1) by CPE reduction assay in three different layouts to elucidate virucidal, post-exposure and preexposure antiviral activity of the extracts. The cold and hot aqueous extracts of bark and hot aqueous extract of leaves of E. jambolana showed significant virucidal activity (100% inhibition) which was further confirmed in virus yield reduction assay (-98 to 99% reduction) and by egg based in ovo assay. The selective index (CC50/EC50) of hot aqueous extract (248) and cold aqueous extract (43.5) of bark of E. jambolana showed their antiviral potential against H5N1 virus. The significant virucidal activity of leaves and bark of E. jambolana merits further investigation as it may provide alternative antiviral agent for managing avian influenza infections in poultry farms and potential avian-human transmission.
Not Available
 
Date 2018-03-22T07:23:40Z
2018-03-22T07:23:40Z
2012-03-01
 
Type Research Paper
 
Identifier Sood, R., Swarup, D., Bhatia, S., Kulkarni, D.D., Dey, S., Saini, M., and Dubey, S. C. (2012). Antiviral activity of crude extracts of Eugenia jambolana Lam. against Highly pathogenic avian influenza (H5N1) virus. Indian J Exp Biol. 2012 Mar;50(3):179-86
0975-1009
http://krishi.icar.gov.in/jspui/handle/123456789/5952
 
Language English
 
Relation Not Available;
 
Publisher NISCAIR-CSIR, India