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Isolation and genetic characterization of influenza A (subtype H5N1) virus from crows in India.

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Title Isolation and genetic characterization of influenza A (subtype H5N1) virus from crows in India.
Not Available
 
Creator Das B.R.
Tosh C.
Kumar M.
Nagarajan S.
Murugkar H.V.
Shukla S.
Tripathi S.
Mishra A.
Kulkarni D.
 
Subject Highly Pathogenic Avian Influenza (HPAI)
HPAI virus
subtype H5N1
Crow
Phylogeny
 
Description Not Available
We isolated two influenza A (subtype H5N1) viruses from crows in India, in 2011
and 2012. Nucleotide sequence of all eight genome segments of both the viruses (A/crow/India/
11TI07/2011 and A/crow/India/01TR01/2012) was determined and used for analysis. The two isolates
shared >99% nucleotide sequence identity in all the eight genes. Phylogenetic analysis revealed
that both the viruses belonged to haemagglutinin (HA) clade 2.3.2.1 of H5N1 viruses. Within clade
2.3.2.1, the crow viruses grouped with contemporary H5N1 viruses isolated from poultry in India;
poultry, crows and environmental sampleas in Bangladesh; and poultry and wild birds in Bhutan. The
viruses have the characteristic feature of high pathogenicity to chickens, and possessed avian-like
(α 2, 3-linked sialic acid) receptor-specificity in the HA. Analysis of amino acid sequences in the
neuraminidase (NA) and M2 indicated that the crow viruses are susceptible to currently available
influenza drugs.
Not Available
 
Date 2018-03-22T07:48:29Z
2018-03-22T07:48:29Z
2014-11-01
 
Type Research Paper
 
Identifier Das BR, Tosh C, Kumar M, Nagarajan S, Murugkar HV, Shukla S, Tripathi S, Mishra A, Kulkarni D (2014). Isolation and genetic characterization of influenza A (subtype H5N1) virus from crows in India. Adv. Anim. Vet. Sci. 2 (11): 620-624.
2307-8316
http://krishi.icar.gov.in/jspui/handle/123456789/5972
 
Language English
 
Relation Not Available;
 
Publisher Nexus Academic Publishers