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Viral Metagenomics: A Review

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Title Viral Metagenomics: A Review
Not Available
 
Creator Fawaz M.
Raut A.A.
Mishra A.
Kamble N.
Vijaykumar P.
 
Subject Next generation sequencing
Molecular diagnostics
Sequencing platforms
 
Description Not Available
Sequencing technology has shown significant improvement since its
first installment in 1977 by Frederick Sanger and colleagues. The Human
Genome Project resulted in great refinement of sequencing technology with
many promising discoveries. These newer sequencing technologies are
called the Next Generation Sequencing (NGS) technologies. Public Health
and Veterinary scientists started picking up NGS technology in a number of
animal disease diagnosis including the discovery of Schmallenberg viruses.
A review on the use of NGS technology in animal disease diagnosis
including discovery of novel microbes, differentiation of various
pathotypes, evolutionary aspect of microbes and host-pathogen interaction,
transcriptomics (RNA-sequencing), disease surveillance etc. is dealt with in
here. With the continuous decent in the cost of DNA sequencing it is
estimated that NGS would become the gold standard in the molecular
diagnosis of animal diseases. What has to be undermined is that most of the
efforts in the area of animal disease diagnosis related to NGS stops once a
novel microbe or evolutionary pattern has been identified without further
studies on the pathogenicity and related effects on the host.
Not Available
 
Date 2018-03-22T07:50:33Z
2018-03-22T07:50:33Z
2014-12-01
 
Type Research Paper
 
Identifier Fawaz M, Raut AA, Mishra A, Kamble N, Vijaykumar P (2014). Viral Metagenomics: A Review. Vet. Res. Int October-December, 2014 Vol 2 Issue 4 Pages 81-89.
2347 - 5773
http://krishi.icar.gov.in/jspui/handle/123456789/5988
 
Language English
 
Relation Not Available;
 
Publisher JAKRAYA AN ACADEMIC and SCIENTIFIC PUBLISHER