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Serological evidence of widespread West Nile virus and Japanese encephalitis virus infection in native domestic ducks (Anasplatyrhynchos var domesticus) in Kuttanad region, Kerala, India

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Title Serological evidence of widespread West Nile virus and Japanese encephalitis virus infection in native domestic ducks (Anasplatyrhynchos var domesticus) in Kuttanad region, Kerala, India
Not Available
 
Creator Kalaiyarasu S.
Mishra N.
Khetan R.K.
Singh V.P.
 
Subject Domestic ducks
India
Japanese encephalitis virus
Kerala
Neutralizing antibodies
West Nile virus
 
Description Not Available
Birds can act as reservoirs of West Nile virus (WNV) with a key role in its epidemiology. WNV lineage 1 associated fatal cases of human encephalitis in 2011 and acute flaccid paralysis in 2013 were reported in Alappuzha district, Kerala, India. But no information is available on WNV circulation in domestic ducks, which are abundant, cohabit with humans and occupy wetlands and water bodies in the region. To determine the extent of WNV infection, we investigated 209 sera, 250 oral and 350 cloacal swab samples from local Chara and Chemballi domestic ducks (Anas platyrhynchos var domesticus) in the districts of Alappuzha, Kottayam, Kollam and Pathanamthitta collected during January and March 2015. The serum samples were tested for WNV antibodies first by a competition ELISA and then by a micro virus neutralization test (micro-VNT), while oral and cloacal swabs were subjected to WNV real-time RT-PCR. Ninety five ducks showed evidence of flavivirus antibodies by ELISA. End point neutralizing antibody titre against WNV and Japanese encephalitis virus (JEV) revealed WNV specific antibodies in 24 (11.5%) ducks in 3 districts, JEV specific antibodies in 21 (10%) ducks in 2 districts and flavivirus specific antibodies in 19 (9%) ducks. However, no WNV genomic RNA could be detected. The results of this study demonstrate evidence of widespread WNV and JEV infection in domestic ducks in Kuttanad region, Kerala with a higher seroprevalence to WNV than JEV. Additionally, it highlights the utility of domestic ducks as a surveillance tool to detect WNV/JEV circulation in a region.
Not Available
 
Date 2018-03-22T07:54:39Z
2018-03-22T07:54:39Z
1001-01-01
 
Type Research Paper
 
Identifier Kalaiyarasu S, Mishra N, Khetan R.K, Singh V.P. (2016). Serological evidence of widespread West Nile virus and Japanese encephalitis virus infection in native domestic ducks (Anasplatyrhynchos var domesticus) in Kuttanad region, Kerala, India. Comp Immunol Microbiol Infect Dis. 2016 Oct;48:61-8.
0147-9571
http://krishi.icar.gov.in/jspui/handle/123456789/6018
 
Language English
 
Relation Not Available;
 
Publisher Elsevier B.V.