Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India.
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Title |
Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India.
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Creator |
Ganar K.
Das M. Raut A.A. Mishra A. Kumar S. |
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Subject |
Pigeon paramyxovirus
Paramyxovirus type 1 Pathogenic characterization PPMV-1 |
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Description |
Not Available
Pigeon paramyxovirus type 1 (PPMV-1) is an antigenic variant of avian paramyxovirus type 1 (APMV-1), which infects pigeons. The virus causes high morbidity and mortality, creating an alarming state for the poultry industry. The present work describes the molecular and pathogenic characterization of a PPMV-1 strain isolated from pigeon in Bhopal, India. Complete genome sequence analysis revealed a genome of 15,192 nucleotides encoding six genes organized in the order 3'-N-P-M-F-HN-L-5'. The fusion gene sequence analysis showed the presence of multiple basic amino acids 112R-R-Q-K-R-F117 at the cleavage site corresponding to pathogenic strains. The mean death time and intracerebral pathogenicity index values indicated a mesogenic nature for the PPMV-1 isolate. On phylogenetic analysis, the strain clustered with genotype VI viruses, including isolates from pigeon and dove. The Bhopal strain showed significant intra and inter-genotype evolutionary distance, suggesting the emergence of a new sub-genotype, VIj. Not Available |
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Date |
2018-03-22T07:55:07Z
2018-03-22T07:55:07Z 2017-03-01 |
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Type |
Research Paper
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Identifier |
Ganar K, Das M, Raut AA, Mishra A, Kumar S. 2017. Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India. Arch Virol. 2017 Mar 27.
0304-8608 http://krishi.icar.gov.in/jspui/handle/123456789/6021 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Springer Vienna
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