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Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India.

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Title Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India.
 
Creator Ganar K.
Das M.
Raut A.A.
Mishra A.
Kumar S.
 
Subject Pigeon paramyxovirus
Paramyxovirus type 1
Pathogenic characterization
PPMV-1
 
Description Not Available
Pigeon paramyxovirus type 1 (PPMV-1) is an antigenic variant of avian paramyxovirus type 1 (APMV-1), which infects pigeons. The virus causes high morbidity and mortality, creating an alarming state for the poultry industry. The present work describes the molecular and pathogenic characterization of a PPMV-1 strain isolated from pigeon in Bhopal, India. Complete genome sequence analysis revealed a genome of 15,192 nucleotides encoding six genes organized in the order 3'-N-P-M-F-HN-L-5'. The fusion gene sequence analysis showed the presence of multiple basic amino acids 112R-R-Q-K-R-F117 at the cleavage site corresponding to pathogenic strains. The mean death time and intracerebral pathogenicity index values indicated a mesogenic nature for the PPMV-1 isolate. On phylogenetic analysis, the strain clustered with genotype VI viruses, including isolates from pigeon and dove. The Bhopal strain showed significant intra and inter-genotype evolutionary distance, suggesting the emergence of a new sub-genotype, VIj.
Not Available
 
Date 2018-03-22T07:55:07Z
2018-03-22T07:55:07Z
2017-03-01
 
Type Research Paper
 
Identifier Ganar K, Das M, Raut AA, Mishra A, Kumar S. 2017. Emergence of a deviating genotype VI pigeon paramyxovirus type-1 isolated from India. Arch Virol. 2017 Mar 27.
0304-8608
http://krishi.icar.gov.in/jspui/handle/123456789/6021
 
Language English
 
Relation Not Available;
 
Publisher Springer Vienna