ICAR Research Data Repository for Knowledge Management
Promoter variants at AP2 box region of Hsp70.1 affect thermal stress response and milk production traits in Frieswal cross bred cattle
KRISHI: Publication and Data Inventory Repository
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| Title |
Promoter variants at AP2 box region of Hsp70.1 affect thermal stress response and milk production traits in Frieswal cross bred cattle
Not Available |
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| Creator |
Deb R, Sajjanar B, Singh U, Kumar S, Brahmane MP, Singh R, Sengar G, Sharma A
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| Subject |
Not Available
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| Description |
Not Available
Heat shock proteins (Hsp) are known to play major role in protection of cells from thermal stress. Nucleotide polymorphisms within the promoter of Hsp affect degree of expression and inducibility of Hsp mRNA. The present study aimed to investigate the effect of polymorphism within promoter region on the cellular expression of Hsp70.1 mRNA and association of identified polymorphisms with the physiological parameters during summer stress and milk production traits in dairy cattle. Two hundred Frieswal cows were genotyped using double PCR-RFLP to identify deletion of cytosine within the Hsp70.1 promoter AP2 box at base position 895. Homozygous wild type genotypes (CC) were found in lower frequency (39.29, n=78) than heterozygous cytosine deletion mutant genotypes (C-) (60.71, n=122). In the observed physiological parameters (rectal temperature, respiration rate and heat tolerance coefficient), cows that were homozygous wild types had better significant (P Not Available |
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| Date |
2017-07-01T05:00:48Z
2017-07-01T05:00:48Z 2013-12-01 |
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| Type |
Research Paper
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| Identifier |
18
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/4571 |
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| Language |
English
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| Relation |
Not Available;
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| Publisher |
Elseiver
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