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Effect of long term fluoride toxicity on immunity and pathology in Wistar albino rat

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Title Effect of long term fluoride toxicity on immunity and pathology in Wistar albino rat
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Creator Krishnamoorthy P
Gowda NKS
Vallesha NC
Rajendran D
Maya G
Verma S
Raghavendra A
Rahman H
 
Subject Cell mediated immunity, fluoride toxicity, humoral immunity, pathology, rat
 
Description Not Available
The aim of the present study was to assess the effect of fluoride toxicity on immunity and pathology of tissues in Wistar rats. Forty eight male Wistar albino rats aged 8 to 12 weeks were divided into four groups of twelve rats each. The group A, B, C and D were given normal water, 10 ppm, 30 ppm and 60 ppm of fluoride (Sodium fluoride), respectively daily in drinking water. At three, six and nine months of inducing fluoride toxicity, rats were injected with sheep red blood cells. Blood was collected after 14 days of injecting sheep red blood cells to assess humoral immunity. At nine months heparinised blood was used to assess cell mediated immunity. At three, six and nine months, rats were sacrificed and tissues collected for pathological study. Group D showed significant (P
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Date 2018-09-15T05:22:26Z
2018-09-15T05:22:26Z
2014-11-07
 
Type Research Paper
 
Identifier Not Available
0973-970X
http://krishi.icar.gov.in/jspui/handle/123456789/6872
 
Language English
 
Relation Not Available;
 
Publisher Indian Association of Veterinary Pathologists