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Influence of detoxified neem cake on diet digestibility, body weight change, hormonal profiles, immune response and testicular gene expression in male sheep

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Title Influence of detoxified neem cake on diet digestibility, body weight change, hormonal profiles, immune response and testicular gene expression in male sheep
 
Creator Rao SBN
Jash S
Dineshkumar D
Krishnamoorthy P
Elangovan AV
Sivaram M
Parthipan S
Selvaraju S
 
Subject Detoxified neem seed cake Growing sheep Hormonal profiles Gene expression
 
Description Not Available
The present study was conducted to find out the effect of supplementing defatted and
detoxified neem (Azadirachta indica) seed cake as a partial replacement of soybean meal
(SBM) in the diet of growing lambs. Male lambs of uniform body weight (8.31 ± 0.32 kg)
were randomly allotted to three groups such as control (diet containing SBM) and two test
diets with defatted and detoxified neem cake (DNC) at two levels (34 g and 68 g per kg of
diet) replacing 25% and 50% nitrogen of SBM (DNC-25 and DNC-50). The respective diets
(concentrate mixtures along with finger millet (Eleucine corocana) straw) were fed individually
to lambs for a period of 140 days. The repeated measure ANOVA indicated that lambs
on DNC treatments grew on par with control across all the periods and no interaction was
observed. The difference in the dry matter intake was not found to be significant (P > 0.05)
in any of the three study groups. Similarly apparent nutrient digestibility, nitrogen balance,
rumen and hormonal profiles did not differ (P > 0.05) across the groups. Humoral and cell
mediated immune response measured in terms of antibody titre and lymphocyte proliferation
assay was also the same (P > 0.05) across the groups. The relative gene expression
of IGF-I and LHR transcripts in testes tissue was positively influenced (P < 0.05) in DNC-50
treatment (3–4 fold increase) as compared to control and DNC-25. No histopathological
changes were observed in vital organs of sheep fed DNC diets compared to control. It can
be concluded that based on the studied parameters, DNC can replace 50% of SBM nitrogen
with 3–4 fold increase in gene expression in testes tissue.
DBT funded project
 
Date 2018-09-15T07:08:06Z
2018-09-15T07:08:06Z
2015-10-17
 
Type Research Paper
 
Identifier Not Available
0377-8401
http://krishi.icar.gov.in/jspui/handle/123456789/6890
 
Language English
 
Relation Not Available;
 
Publisher Elsevier Publications