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Boron supplementation provides hepato-protective effect and improves performance in Wistar rats fed with calcium deficient diet

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Title Boron supplementation provides hepato-protective effect and improves performance in Wistar rats fed with calcium deficient diet
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Creator Bhasker TV
Gowda NKS
Krishnamoorthy P
Pal DT
Sejian V
Awachat VB
Pattanaik AK
Verma AK
 
Subject Boron, Calcium, Hepato-protection, Histopathology, Nutrient utilization, Wistar rats
 
Description Not Available
This study was conducted to investigate the influence of boron (B) supplementation in rats fed diets with
adequate and deficit calcium (Ca). A feeding trial of 90 days duration was conducted in 84 Wistar strain rats
divided into 7 groups, viz. Normal-Ca (100%) basal diet (NC) and supplemented with B at 5 (NCB-5), 10 (NCB-
10), 20 (NCB-20) and 40 (NCB-40) ppm levels; low-Ca (50%) diet (LC) and supplemented with 40 ppm B (LCB-
40). During 80–85 days of feeding, a digestibility trial was conducted to record nutrient digestibility. Rats (8) from each group were sacrificed to collect blood and visceral organs to study biochemical parameters and histopathology. The average daily feed and water intake were similar among the dietary groups. Body weight gain was lower in rats fed LC diet and increased in the LCB-40 group. Nutrient (dry matter, crude protein, crude fat) digestibility was significantly improved with B-supplementation to NC diets. Serum levels of triglycerides, HDL-cholesterol and alanine transaminase were significantly lowered in B-supplemented groups. The levels of glucose, total cholesterol, alkaline phosphatase and aspartate transaminase in serum remained unaltered among the dietary groups. Degenerative changes were observed in the liver of rats fed Ca-deficient diets and were ameliorated with 40 ppm B supplementation. Results indicated that dietary supplementation of B in rats showed improved nutrient digestibility, growth and lowered serum levels of triglycerides, HDL-cholesterol and alanine transaminase. Hepatic tissue alterations due to lower Ca intake were ameliorated with B supplementation.
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Date 2018-09-18T04:34:41Z
2018-09-18T04:34:41Z
2017-10-27
 
Type Research Paper
 
Identifier Not Available
0367-8318
http://krishi.icar.gov.in/jspui/handle/123456789/6945
 
Language English
 
Relation Not Available;
 
Publisher Indian Council of Agricultural Research