Effect of long term toxicity on immunity and pathology in wister albino rats
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Title |
Effect of long term toxicity on immunity and pathology in wister albino rats
Not Available |
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Creator |
Krishnamoorthy P,
Gowda NKS, Vallesha NC, Rajendran D, Maya G, Verma S, Raghavendra A Rahman H. |
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Subject |
Cell mediated immunity
fluoride toxicity humoral immunity pathology rat |
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Description |
Not Available
The aim of the present study was to assess the effect of fluoride toxicity on immunity and pathology of tissues in Wistar rats. Forty eight male Wistar albino rats aged 8 to 12 weeks were divided into four groups of twelve rats each. The group A, B, C and D were given normal water, 10 ppm, 30 ppm and 60 ppm of fluoride (Sodium fluoride), respectively daily in drinking water. At three, six and nine months of inducing fluoride toxicity, rats were injected with sheep red blood cells. Blood was collected after 14 days of injecting sheep red blood cells to assess humoral immunity. At nine months heparinised blood was used to assess cell mediated immunity. At three, six and nine months, rats were sacrificed and tissues collected for pathological study. Group D showed significant (P ICAR |
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Date |
2018-11-18T16:54:34Z
2018-11-18T16:54:34Z 2014-01-01 |
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Type |
Research Paper
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Identifier |
Krishnamoorthy P, Gowda NKS, Vallesha NC, Rajendran D, Maya G, Verma S, Raghavendra A and Rahman H. 2014. Effect of long term toxicity on immunity and pathology in wister albino rats. Indian Journal of Veterinary Pathology, 38:164-168.
0250-4758 http://krishi.icar.gov.in/jspui/handle/123456789/11838 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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