Effect of bone morphogenetic protein-2 (BMP-2) on sheep granulosa cell steroidogenic function
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Title |
Effect of bone morphogenetic protein-2 (BMP-2) on sheep granulosa cell steroidogenic function
Not Available |
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Creator |
Vinod Kumar D
Gulzar R Selvaraju S Nazar S Parthipan S Anand Prasad RV Jamuna KV Ravindra JP |
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Subject |
Bone morphogenetic protein-2 (BMP-2)
Granulosa cell Estradioal |
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Description |
Not Available
The bone morphogenetic protein-2 (BMP-2) has been implicated in follicle growth and steroidogenic functions of the ovary. The BMP-2 belongs to the BMPs subfamily of TGF-β superfamily. The present study was carried out in sheep granulosa cell culture to study the effect of different doses ofBMP-2 0ng/ml (control group), 30ng/ml, 50ng/ml and 100ng/ml on granulosa cell steriodogenic function. For functional studies, granulosa cells were obtained from ovarian follicles 1–3 mm in diameter. The cells were cultured for 6 daysin serum-free medium containing androstenedione and LR3-IGF-I. The medium was replaced for every two days and the spent medium was used to assess the concentration of estradiol 17-β in cultured granulosa cells by radioimmunoassay. The BMP-2 at all the three different doses increased the estradioal 17-β production when compared to control group of treatment (P Not Available |
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Date |
2018-11-22T22:58:30Z
2018-11-22T22:58:30Z 2014-01-01 |
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Type |
Research Paper
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Identifier |
Vinod Kumar D, Gulzar R, Selvaraju S, Nazar S, Parthipan S, Anand, Prasad RV, Jamuna KV and Ravindra JP. 2014. Effect of bone morphogenetic protein-2 (BMP-2) on sheep granulosa cell steroidogenic function. Journal of Cell and Tissue Research, 14:4233-4236.
0973-0028 http://krishi.icar.gov.in/jspui/handle/123456789/12859 |
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Language |
English
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Relation |
Not Available;
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Publisher |
CTR Publications
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