Boron and calcium chloride as possible ameliorators of fluoride toxicity in Wistar rats
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Title |
Boron and calcium chloride as possible ameliorators of fluoride toxicity in Wistar rats
Not Available |
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Creator |
Gowda NKS
Rajendran D Krishnamoorthy P Vallesha NC Raghavendra A Awachat VB Maya G Verma S |
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Subject |
Fluorosis
Livestock Mineral profile |
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Description |
Not Available
Fluorosis is an endemic health problem for both humans and livestock in some parts of the world including India. This fast expanding problem needs remedial measures. Though limited reports suggest ameliorative effect of boron (B) and calcium (Ca) against fluoride (F) toxicity in animals, still there is a need for long duration study to understand the possible mechanism of action. Here, we did the same; studied the ameliorative effect of B and Ca on F toxicity in Wistar strain (Rattus norvegicus) rats. Forty-eight male Wistar albino rats were divided randomly into six groups. The group T1 was given normal water (control) while the groups T2-T6 were supplemented with F through water @ 30 ppm (as sodium fluoride), 30 ppm F+ 50 ppm B (as sodium borate), 50 ppm B, 30 ppm F+ 50 ppm calcium chloride and 50 ppm calcium chloride, respectively. After four months, all the rats were sacrificed and blood, teeth, femur bone and liver were collected and analyzed for mineral content. Fluoride toxicity significantly (P Not Available |
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Date |
2018-11-24T16:37:59Z
2018-11-24T16:37:59Z 2017-01-01 |
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Type |
Research Paper
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Identifier |
Gowda NKS, Rajendran D, Krishnamoorthy P, Vallesha NC, Raghavendra A, Awachat VB, Maya G and Verma S. 2017. Boron and calcium chloride as possible ameliorators of fluoride toxicity in Wistar rats. Indian Journal of Experimental Biology, 55:864-869.
0975-1009 http://krishi.icar.gov.in/jspui/handle/123456789/13182 |
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Language |
English
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Relation |
Not Available;
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Publisher |
CSIR
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