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Advances in peste des petits ruminants vaccines

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Title Advances in peste des petits ruminants vaccines
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Creator Naveen Kumar*, Sanjay Barua*, Thachamvally Riyesh, Bhupendra N. Tripathi
 
Subject Peste des petits ruminants, PPR Vaccine, Recombinant vaccines, Thermostable vaccine
 
Description Not Available
Peste des petits ruminants (PPR) is a highly contagious disease of small ruminants that leads to high
morbidity and mortality thereby results in devastating economic consequences to the livestock industry.
PPR is currently endemic across most parts of Asia and Africa, the two regions with the highest
concentration of poor people in the world. Sheep and goats in particularly contribute significantly
towards the upliftment of livelihood of the poor and marginal farmers in these regions. In this context,
PPR directly affecting the viability of sheep and goat husbandry has emerged as a major hurdle in the
development of these regions. The control of PPR in these regions could significantly contribute to
poverty alleviation, therefore, the Office International des Epizooties (OIE) and Food and Agricultural
Organization (FAO) have targeted the control and eradication of PPR by 2030 a priority. In order to achieve
this goal, a potent, safe and efficacious live-attenuated PPR vaccine with long-lasting immunity is
available for immunoprophylaxis. However, the live-attenuated PPR vaccine is thermolabile and needs
maintenance of an effective cold chain to deliver into the
field. In addition, the infected animals cannot be
differentiated from vaccinated animals. To overcome these limitations, some recombinant vaccines have
been developed. This review comprehensively describes about the latest developments in PPR vaccines.
Not Available
 
Date 2018-11-29T05:17:45Z
2018-11-29T05:17:45Z
2017-01-12
 
Type Article
 
Identifier N. Kumar, et al., Advances in peste des petits ruminants vaccines, Vet. Microbiol. (2017), http://dx.doi.org/ 10.1016/j.vetmic.2017.01.010 Contents lists available at ScienceDirect Veterinary Microbiology journal homepage: www.else vie r.com/locate /ve
0378-1135
http://krishi.icar.gov.in/jspui/handle/123456789/13945
 
Language English
 
Relation Not Available;
 
Publisher ELSEVIER