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Isolation and characterization of a bacteriophage with broad host range, displaying potential in preventing bovine diarrhoea.

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Title Isolation and characterization of a bacteriophage with broad host range, displaying potential in preventing bovine diarrhoea.
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Creator Anand T, Vaid RK, Bera BCh, Barua S, Riyesh T, Virmani N, Yadav N, Malik P.
 
Subject Bacteriophage, Electron microscopy, Myoviridae, Diarrhoea, E. coli
 
Description Not Available
Phage therapy has been previously tried for treatment of diarrhoea in calves,
pigs and lambs but those trials were conducted without any detailed information
of used phages. Here, we report isolation of a broad-spectrum phage which showed
bactericidal activity against 47.3 % of calf diarrhoeal isolates of Escherichia
coli, in vitro. The isolated phage resembled the characteristics of Myoviridae
family and showed ~97 % similarity with earlier reported bacteriophages of sub
family-Tevenvirinae, genus-T4-like virus, based on nucleotide sequence of major
head protein-gp23 gene. The phage exhibits the potential to be used as drug
substitute tool against E. coli causing diarrhoea in cattle in farm environments.
Not Available
 
Date 2018-11-29T10:25:48Z
2018-11-29T10:25:48Z
2015-07-15
 
Type Journal
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/14169
 
Language English
 
Relation Not Available;
 
Publisher Not Available