Isolation and characterization of a bacteriophage with broad host range, displaying potential in preventing bovine diarrhoea.
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Title |
Isolation and characterization of a bacteriophage with broad host range, displaying potential in preventing bovine diarrhoea.
Not Available |
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Creator |
Anand T, Vaid RK, Bera BCh, Barua S, Riyesh T, Virmani N, Yadav N, Malik P.
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Subject |
Bacteriophage, Electron microscopy, Myoviridae, Diarrhoea, E. coli
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Description |
Not Available
Phage therapy has been previously tried for treatment of diarrhoea in calves, pigs and lambs but those trials were conducted without any detailed information of used phages. Here, we report isolation of a broad-spectrum phage which showed bactericidal activity against 47.3 % of calf diarrhoeal isolates of Escherichia coli, in vitro. The isolated phage resembled the characteristics of Myoviridae family and showed ~97 % similarity with earlier reported bacteriophages of sub family-Tevenvirinae, genus-T4-like virus, based on nucleotide sequence of major head protein-gp23 gene. The phage exhibits the potential to be used as drug substitute tool against E. coli causing diarrhoea in cattle in farm environments. Not Available |
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Date |
2018-11-29T10:25:48Z
2018-11-29T10:25:48Z 2015-07-15 |
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Type |
Journal
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/14169 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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