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Chronic flubendiamide exposure induces oxidative stress in water buffalo (Bubalusbubalis) calves

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Title Chronic flubendiamide exposure induces oxidative stress in water buffalo (Bubalusbubalis) calves
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Creator Ranjan,A.,Dumka,V.K., and Ranjan, R.
 
Subject Buffalo; flubendiamide; insecticide; oxidative-stress; toxicity
 
Description Not Available
Changes in oxidative stress indices in buffalo calves following oral flubendiamide administration @ 0.024 mg/ kg/ day for 90 consecutive days was studied. In flubendiamide administered animals, the lipid peroxides level increased to become 49.38% higher, while glutathione level declined to become 29.32% lower than control on day 90. The plasma total antioxidant capacity declined to a significantly lower level (24.87%) than control. Increase in activities of catalase and glutathione-s-transferase was recorded in flubendiamide treated animals on day 60 onwards, but glutathione peroxidase, glutathione reductase and glucose-6-phosphate dehydrogenase activities revealed declining trend. On day 30 post-treatment, activities of various antioxidant enzymes returned close to pre-treatment level and were statistically comparable to corresponding levels in control group. Results indicated that chronic flubendiamide exposure induces oxidative stress that may play an important role in toxicopathology of this novel insecticide.
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Date 2019-07-22T07:09:04Z
2019-07-22T07:09:04Z
2018-04-01
 
Type Article
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/21619
 
Language English
 
Relation Not Available;
 
Publisher Not Available