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High-density Genotyping reveals Genomic Characterization, Population Structure and Genetic Diversity of Indian Mithun (Bos frontalis)

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Title High-density Genotyping reveals Genomic Characterization, Population Structure and Genetic Diversity of Indian Mithun (Bos frontalis)
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Creator Anupama Mukherjee1,3, Sabyasachi Mukherjee1, Rajan Dhakal 2, Moonmoon Mech1, Imsusosang Longkumer1, Nazrul Haque1, Kezhavituo Vupru1, Kobu Khate1, I. Yanger Jamir1, Pursenla Pongen1, Chandan Rajkhowa1, Abhijit Mitra1, Bernt Guldbrandtsen 2 & Goutam Sahana
 
Subject High-density Genotyping reveals Genomic Characterization, Population Structure and Genetic Diversity of Indian Mithun (Bos frontalis)
 
Description Not Available
The current study aimed at genomic characterization and improved understanding of genetic diversity
of two Indian mithun populations (both farm, 48 animals and field, 24 animals) using genome wide
genotype data generated with Illumina BovineHD BeadChip. Eight additional populations of taurine
cattle (Holstein and NDama), indicine cattle (Gir) and other evolutionarily closely related species (Bali
cattle, Yak, Bison, Gaur and wild buffalo) were also included in this analysis (N = 137) for comparative
purposes. Our results show that the genetic background of mithun populations was uniform with
few possible signs of indicine admixture. In general, observed and expected heterozygosities were
quite similar in these two populations. We also observed increased frequencies of small-sized runs of
homozygosity (ROH) in the farm population compared to field mithuns. On the other hand, longer ROH
were more frequent in field mithuns, which suggests recent founder effects and subsequent genetic
drift due to close breeding in farmer herds. This represents the first study providing genetic evidence
about the population structure and genomic diversity of Indian mithun. The information generated
will be utilized for devising suitable breeding and conservation programme for mithun, an endangered
bovine species in India.
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Date 2019-09-06T04:42:21Z
2019-09-06T04:42:21Z
2018-07-19
 
Type Research Paper
 
Identifier 3
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http://krishi.icar.gov.in/jspui/handle/123456789/22965
 
Language English
 
Relation Not Available;
 
Publisher SCIENTIFIC REPORTS