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Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.

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Title Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.
Not Available
 
Creator Vandana GD
Bagath M
Sejian V
Krishnan G
Beena V
Bhatta R.
 
Subject Climate change
goat
heat stress
immune response
TLRs
 
Description Not Available
The study was conducted with the primary objective of establishing the impact of heat stress on the expression pattern of different toll-like-receptors (TLRs) in Malabari goats. The study was conducted for a period of 45 days using twelve Malabari goats. The goats were randomly allocated into two groups: MC (n = 6; Malabari control) and MHS (n = 6; Malabari heat stress). At the end of study, all 12 animals were slaughtered and their mesenteric lymph node (MLN) tissues were collected for gene expression. Heat stress significantly (p < 0.05) down regulated TLR1, TLR4, TLR5 and TLR6 and significantly increased (p < 0.05) TLR2 expression pattern. A negative correlation (p < 0.01) was also established between THI and different TLRs except TLR3, TLR7 and TLR10. The study indicated that TLR2 could serve as ideal immunological marker for establishing the superior thermo-tolerance ability of Malabari breed in terms of maintaining the immune status during heat stress challenges.
ICAR-NIANP
 
Date 2019-11-15T11:00:46Z
2019-11-15T11:00:46Z
2018-04-23
 
Type Research Paper
 
Identifier Vandana GD, Bagath M, Sejian V, Krishnan G, Beena V, Bhatta R. 2018. Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.
0929-1016
http://krishi.icar.gov.in/jspui/handle/123456789/24809
 
Language English
 
Relation Not Available;
 
Publisher Taylor and Francis