Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.
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Title |
Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.
Not Available |
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Creator |
Vandana GD
Bagath M Sejian V Krishnan G Beena V Bhatta R. |
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Subject |
Climate change
goat heat stress immune response TLRs |
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Description |
Not Available
The study was conducted with the primary objective of establishing the impact of heat stress on the expression pattern of different toll-like-receptors (TLRs) in Malabari goats. The study was conducted for a period of 45 days using twelve Malabari goats. The goats were randomly allocated into two groups: MC (n = 6; Malabari control) and MHS (n = 6; Malabari heat stress). At the end of study, all 12 animals were slaughtered and their mesenteric lymph node (MLN) tissues were collected for gene expression. Heat stress significantly (p < 0.05) down regulated TLR1, TLR4, TLR5 and TLR6 and significantly increased (p < 0.05) TLR2 expression pattern. A negative correlation (p < 0.01) was also established between THI and different TLRs except TLR3, TLR7 and TLR10. The study indicated that TLR2 could serve as ideal immunological marker for establishing the superior thermo-tolerance ability of Malabari breed in terms of maintaining the immune status during heat stress challenges. ICAR-NIANP |
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Date |
2019-11-15T11:00:46Z
2019-11-15T11:00:46Z 2018-04-23 |
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Type |
Research Paper
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Identifier |
Vandana GD, Bagath M, Sejian V, Krishnan G, Beena V, Bhatta R. 2018. Summer season induced heat stress impact on the expression patterns of different Toll-Like Receptor genes in Malabari goats. Biological Rhythm Research, 50:466-482.
0929-1016 http://krishi.icar.gov.in/jspui/handle/123456789/24809 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Taylor and Francis
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