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Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India

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Title Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India
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Creator Souti Prasad Sarkhel, S.K. Gupta, Jyoti Kaushik, Jarnail Singh, Vijesh Kumar Saini, Sanjay Kumar and Rajender Kumar
 
Subject Trypanosoma evansi, Surra, transferrin receptor encoding gene, ESAG, genetic variability, India
 
Description Not Available
Trypanosoma evansi, the aetiological agent of Surra affects a wide range of livestock and wild animals in India. In the present
study, we studied intra- and inter species genetic variability in the transferrin receptor encoding gene regions (ESAG6/7 gene
region) of T. evansi isolates by cloning, sequencing and phylogenetic study collected from camel, cattle, donkeys and ponies
from North-Western and Central India. The nucleotide sequence variation of ESAG6/7 gene region between Indian T. evansi
isolates was up to 17.7% and amino acid sequence variation was up to 31%. Twenty nine clones from six T. evansi isolates from
geographical regions of India were included into Clade 1, 5, 6, 7 and 9 consisting of ESAG6 variants reported among T. evansi
isolates from South-east Asia and South America. The cladogram indicated a relation between the host species and the genetic
variability in the hyper-variable region of ESAG6 gene. Analysis of the Indian ESAG6 variants and their respective Clade positions
presented a host specific distribution indicating homogenous parasite population in their respective animal hosts.
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Date 2019-12-06T06:46:45Z
2019-12-06T06:46:45Z
2017-01-01
 
Type Book
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/28403
 
Language English
 
Relation Not Available;
 
Publisher Springer