Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India
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Title |
Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India
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Creator |
Souti Prasad Sarkhel, S.K. Gupta, Jyoti Kaushik, Jarnail Singh, Vijesh Kumar Saini, Sanjay Kumar and Rajender Kumar
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Subject |
Trypanosoma evansi, Surra, transferrin receptor encoding gene, ESAG, genetic variability, India
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Description |
Not Available
Trypanosoma evansi, the aetiological agent of Surra affects a wide range of livestock and wild animals in India. In the present study, we studied intra- and inter species genetic variability in the transferrin receptor encoding gene regions (ESAG6/7 gene region) of T. evansi isolates by cloning, sequencing and phylogenetic study collected from camel, cattle, donkeys and ponies from North-Western and Central India. The nucleotide sequence variation of ESAG6/7 gene region between Indian T. evansi isolates was up to 17.7% and amino acid sequence variation was up to 31%. Twenty nine clones from six T. evansi isolates from geographical regions of India were included into Clade 1, 5, 6, 7 and 9 consisting of ESAG6 variants reported among T. evansi isolates from South-east Asia and South America. The cladogram indicated a relation between the host species and the genetic variability in the hyper-variable region of ESAG6 gene. Analysis of the Indian ESAG6 variants and their respective Clade positions presented a host specific distribution indicating homogenous parasite population in their respective animal hosts. Not Available |
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Date |
2019-12-06T06:46:45Z
2019-12-06T06:46:45Z 2017-01-01 |
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Type |
Book
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/28403 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Springer
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