Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008–2009 in India
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Title |
Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008–2009 in India
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Creator |
Nitin Virmani
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Subject |
equine influenza
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Description |
Not Available
India faced an epizootic of equine influenza in 2008–2009. The isolated viruses were typed as H3N8 and grouped with the clade 2 viruses of Florida sublineage on the basis of haemagglutinin (HA) gene sequence analysis. This report describes the genetic analysis and selection pressure of matrix (M) and non-structural 1 (NS1) genes of the Indian isolates. All isolates shared 98.41% and 99.54% homology with other clade 2 viruses of Asian origin for M1 and M2 amino acid (aa) sequences, respectively. There were 3 and 4 unique aa residue changes respectively in M1 and M2 proteins in all Asian isolates. Phylogenetic analysis revealed clustering of Indian and Chinese isolates in a separate group designated here as Asian clade for M gene. Indian and Chinese isolates shared homology ranging from 98.17% to 99.08% at aa level. The M and NS1 genes were under negative selection pressure with estimated magnitude of pressure (v) 0.054, 0.581 and 0.30 for M1, M2 and NS1, respectively. Not Available |
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Date |
2019-12-07T09:28:11Z
2019-12-07T09:28:11Z 2011-04-14 |
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Type |
Article
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/28688 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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