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Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008–2009 in India

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Title Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008–2009 in India
Not Available
 
Creator Nitin Virmani
 
Subject equine influenza
 
Description Not Available
India faced an epizootic of equine influenza in 2008–2009. The isolated viruses were typed
as H3N8 and grouped with the clade 2 viruses of Florida sublineage on the basis of
haemagglutinin (HA) gene sequence analysis. This report describes the genetic analysis
and selection pressure of matrix (M) and non-structural 1 (NS1) genes of the Indian
isolates. All isolates shared 98.41% and 99.54% homology with other clade 2 viruses of
Asian origin for M1 and M2 amino acid (aa) sequences, respectively. There were 3 and 4
unique aa residue changes respectively in M1 and M2 proteins in all Asian isolates.
Phylogenetic analysis revealed clustering of Indian and Chinese isolates in a separate
group designated here as Asian clade for M gene. Indian and Chinese isolates shared
homology ranging from 98.17% to 99.08% at aa level. The M and NS1 genes were under
negative selection pressure with estimated magnitude of pressure (v) 0.054, 0.581 and
0.30 for M1, M2 and NS1, respectively.
Not Available
 
Date 2019-12-07T09:28:11Z
2019-12-07T09:28:11Z
2011-04-14
 
Type Article
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/28688
 
Language English
 
Relation Not Available;
 
Publisher Not Available