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Comparative genomic organisation of camel beta casein gene promoter: A computational gene regulation study

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Title Comparative genomic organisation of camel beta casein gene promoter: A computational gene regulation study
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Creator SK Bhure, SC Mehta, S Raghavendar
 
Subject Comparative genomic organisation of camel beta casein gene promoter: A computational gene regulation study
 
Description Not Available
Camel milk proteins have pronounced differences in quantitative distribution of caseins as compared with other species. We have analysed the structural organisation of beta-CSNGP 5 '-flanking sequences of camel, bovine and porcine species. The camel beta-CSNGP comprised of 1763bp of 5 '-flanking region and 36bp of exon 1 sequence. The regulatory elements are distributed in 4 clusters between -1270 to -961, -892 to -650, 523 to -230 and -152 to -11. The basal promoter showed the presence of TATA box, CAAT box, binding motifs for OcT 1, Oct 2, Oct 4, AP2, GR half, YY1, C/EBP and MGF/STAT5. The promoter had insertional sequences which are shown to be the binding sites for C/EBP and PRL. A camel beta-casein enhancer region at -1762 to -1371 showed presence of transcription factor binding motifs for C/EBP, MGF/STAT5, GR half, Oct2, Oct3, AP1 and SP1. The overall comparison of structural …
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Date 2020-01-07T09:47:27Z
2020-01-07T09:47:27Z
2008-06-01
 
Type Article
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/29366
 
Language English
 
Relation Not Available;
 
Publisher CAMEL PUBL HOUSE