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Phylogenetic analysis of immunomodulatory protein genes of camel pox virus obtained from India.

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Title Phylogenetic analysis of immunomodulatory protein genes of camel pox virus obtained from India.
Not Available
 
Creator Nagarajan G
Swami SK
Dahiya SS
Sivakumar G
Yadav VK
Tuteja FC
Narnaware SD
Patil NV
 
Subject Camelpoxvirus
Haemagglutinin
encoding
gene
Immunomodulatory
protein
genes
Phylogenetic
analysis
India
 
Description Not Available
The haemagglutinin (HA) encoding gene and genes encoding for immunomodulatory proteins i.e., schlafen-like protein, epidermal growth factor and golgi anti apoptotic protein of camelpoxvirus (CMLV) obtained from Indian dromedarian camels were cloned and characterized. In this study, the size of the HA encoding gene obtained from the Indian CMLV is 941 bp which is only partial. Sequence analysis of schlafen-like protein gene revealed that CMLV obtained from India shared 99.6% identity with CMLV-Iran and CMLV-Kazakhstan strains both at nucleotide and amino acid level. The size of epidermal growth factor (EGF) gene of Indian CMLV obtained in this study was 418 bp, which was due to the addition of one cytosine residue position 132 of EGF gene of Indian CMLV. Sequence analysis revealed that the Golgi anti-apoptotic protein (GAAP) of Indian CMLV shared 99.5% sequence identity both at the nucleotide and amino acid level with CMLV-Kazakhstan. Based on the nucleotide and amino acid sequence identities and phylogenetic analyses of these genes, it is found that CMLV-India is forming a cluster with Kazakhstan and Iranian CMLV isolates.
Not Available
 
Date 2020-02-12T04:58:06Z
2020-02-12T04:58:06Z
2013-01-01
 
Type Article
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/31802
 
Language English
 
Relation Not Available;
 
Publisher Not Available