Characterization of GM-CSF-inhibitory factor and Uracil DNA glycosylase encoding genes from camel pseudocowpoxvirus
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Title |
Characterization of GM-CSF-inhibitory factor and Uracil DNA glycosylase encoding genes from camel pseudocowpoxvirus
Not Available |
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Creator |
Nagarajan G
Swami SK Dahiya SS Dahiya SS Narnaware SD Mehta SC Singh PK Singh R Tuteja FC Patil NV |
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Subject |
Contagious ecthyma
Dromedary camel GM-CSF-inhibitory factor Parapoxviruses Uracil DNA glycosylase |
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Description |
Not Available
The present study describes the PCR amplification of GM-CSF-inhibitory factor (GIF) and Uracil DNA glycosylase (UDG) encoding genes of pseudocowpoxvirus (PCPV) from the Indian Dromedaries (Camelus dromedarius) infected with contagious ecthyma using the primers based on the corresponding gene sequences of human PCPV and reindeer PCPV, respectively. The length of GIF gene of PCPV obtained from camel is 795 bp and due to the addition of one cytosine residue at position 374 and one adenine residue at position 516, the open reading frame (ORF) got altered, resulting in the production of truncated polypeptide. The ORF of UDG encoding gene of camel PCPV is 696 bp encoding a polypeptide of 26.0 kDa. Comparison of amino acid sequence homologies of GIF and UDG of camel PCPV revealed that the camel PCPV is closer to ORFV and PCPV (reference stains of both human and reindeer), respectively. Not Available |
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Date |
2020-02-12T05:01:54Z
2020-02-12T05:01:54Z 2015-01-01 |
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Type |
Article
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Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/31808 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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