Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
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Title |
Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
Not Available |
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Creator |
Anand K
Subhasmita B Saminathan M Sreedharan K Suresh B Reddy GBM Madhusudan H |
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Subject |
3D protein
Foot-and-mouth disease virus Monoclonal antibody |
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Description |
Not Available
Foot-and-mouth disease (FMD) is a major viral disease in farm animals. In the present study, seven monoclonal antibodies (mAbs) were produced against the FMD virus (FMDV)-encoded RNA-dependent RNA polymerase (3D protein) and characterized. Screening of mAb reactivity against three overlapping fragments of the 3D protein expressed in Escherichia coli revealed that the binding sites of all the mAbs were confined to the N-terminal one-third of the 3D protein. A selected mAb was utilized for detecting FMDV in the infected cell culture and tissues obtained from FMDV-infected animals. Not Available |
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Date |
2021-04-19T09:15:57Z
2021-04-19T09:15:57Z 2020-11-17 |
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Type |
Research Paper
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Identifier |
Anand K, Subhasmita B, Saminathan M, Sreedharan K, Suresh B, Reddy GBM and Madhusudan H. (2020). Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection. Microbiology and Immunology. 65(2): 95-98. doi: 10.1111/1348-0421.12860.
1348-0421 http://krishi.icar.gov.in/jspui/handle/123456789/46521 |
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Language |
English
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Relation |
Not Available;
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Publisher |
The Societies and John Wiley & Sons Australia, Ltd
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