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Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.

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Title Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
Not Available
 
Creator Anand K
Subhasmita B
Saminathan M
Sreedharan K
Suresh B
Reddy GBM
Madhusudan H
 
Subject 3D protein
Foot-and-mouth disease virus
Monoclonal antibody
 
Description Not Available
Foot-and-mouth disease (FMD) is a major viral disease in farm animals. In the present study, seven monoclonal antibodies (mAbs) were produced against the FMD virus (FMDV)-encoded RNA-dependent RNA polymerase (3D protein) and characterized. Screening of mAb reactivity against three overlapping fragments of the 3D protein expressed in Escherichia coli revealed that the binding sites of all the mAbs were confined to the N-terminal one-third of the 3D protein. A selected mAb was utilized for detecting FMDV in the infected cell culture and tissues obtained from FMDV-infected animals.
Not Available
 
Date 2021-04-19T09:15:57Z
2021-04-19T09:15:57Z
2020-11-17
 
Type Research Paper
 
Identifier Anand K, Subhasmita B, Saminathan M, Sreedharan K, Suresh B, Reddy GBM and Madhusudan H. (2020). Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection. Microbiology and Immunology. 65(2): 95-98. doi: 10.1111/1348-0421.12860.
1348-0421
http://krishi.icar.gov.in/jspui/handle/123456789/46521
 
Language English
 
Relation Not Available;
 
Publisher The Societies and John Wiley & Sons Australia, Ltd