ICAR Research Data Repository for Knowledge Management
Immunoregulatory response of Lactobacillus helveticus fermented milk in mice
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
Immunoregulatory response of Lactobacillus helveticus fermented milk in mice
Not Available |
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| Creator |
Kapila, S., Jain, S., Haque, E., Sabikhi, L., Dang, A.K.
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| Subject |
Immunomodulatory, Fermented milk, Lactobacillus helveticus
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| Description |
Not Available
The present investigation was carried out to evaluate the immunoregulatory potential of Lactobacillus helveticus fermented milk and its cell free supernatant in mice. Allergic conditions were induced in mice by injecting ovalbumin intraperitoneally on day zero and 14. The mice were divided into four groups and fed milk, L. helveticus fermented milk and its cell free supernatant for a period of 21 days and compared with an allergic control group, respectively. It was observed that on feeding fermented milk and cell free supernatant the production of total IgE and ovalbumin-specific IgE in serum declined significantly in comparison to allergic as well as milk controls. The splenocytes were cultured and cytokines were estimated by ELISA kits. It was observed that levels of Th1 (T helper Type1) cytokines increased whereas the levels of Th2 (T helper Type2) cytokines decreased. Thus decline in IgE production was associated with increase in production of Th1 (IFN-Y, IL-2) cytokines and decrease in Th2 (IL-4, IL-6) cytokines. Not Available |
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| Date |
2021-08-02T08:22:34Z
2021-08-02T08:22:34Z 2008-01-01 |
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| Type |
Research Paper
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| Identifier |
4
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/52074 |
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| Language |
English
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| Relation |
Not Available;
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| Publisher |
Agrar-Verlag Allgaü
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